PACS2 polyclonal (C-term), anti-human

PACS2 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP13142B
Catalog Number: AC-AP13142B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32549
Applications: IHC-P, WB
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Background:
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Other Names:
Phosphofurin acidic cluster sorting protein 2, PACS-2, PACS1-like protein, PACS2, KIAA0602, PACS1L

Target/Specificity:
This PACS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 642-671 amino acids from the C-terminal region of human PACS2.

Antigen Region:
642-671

Antigen Type: Synthetic Peptide

Gene Name: PACS2 (HGNC:23794)
Gene ID: 23241
Primary Accession: Q86VP3
NCBI Accession: NP_001094383.2;NP_001230056.1;NP_056012.2
Other Accession: NP_001094383.1;NP_056012.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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