PACSIN1 polyclonal (Center), anti-human

PACSIN1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP8087c
Catalog Number: AC-AP8087c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3587
Applications: WB, IHC-P
Datasheet

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Background:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Other Names:
Protein kinase C and casein kinase substrate in neurons protein 1, Syndapin-1, PACSIN1, KIAA1379

Target/Specificity:
This PACSIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-38 amino acids from the Central region of human PACSIN1.

Antigen Region:
8-38

Antigen Type: Synthetic Peptide

Gene Name: PACSIN1
Gene ID: 29993
Primary Accession: Q9BY11
NCBI Accession: NP_001186512.1;NP_065855.1
Other Accession: Q9DDA9; Q9QY17; Q9WVE8; Q9UNF0; O13154; Q9Z0W5; Q61644; A7MBI0
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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