PADI4 polyclonal, anti-human

Background:
This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O protein L-citrulline + NH3.

Synonyms: PAD, PAD4, PDI4, PDI5, PADI5

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human PADI4

Gene Symbol: PADI4

Gene ID: 23569

Swiss prot: Q9UM07

Calculated MW: 74kDa

Recommended dilution:
IHC 1:15-50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.