PADI4 Polyclonal Antibody

Background:
This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
EC 3.5.3.15, HL 60 PAD, HL-60 PAD, PAD 4, PAD, PADI 4, PADI 5, PADI H protein, Padi4, PADI4, PADI5, PDI 4, PDI 5, PDI4, PDI5, Peptidyl arginine deiminase type IV, Peptidyl arginine deiminase type V, Peptidylarginine deiminase IV, Protein arginine deiminase, Protein arginine deiminase type 4, Protein arginine deiminase type IV, Protein-arginine deiminase type IV, Protein-arginine deiminase type-4

Immunogen: Fusion protein of human PADI4

Swissprot: Q9UM07
Gene Accession: BC025718

Calculated MW: 74 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.