PAFAH1B1 polyclonal, anti-human

Background:
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. 

Synonyms: LIS 1, LIS1, LIS2, Lissencephaly 1 protein, MDCR, MDS, PAF AH 45 kDa subunit, PAF AH alpha, PAFAH, PAFAH alpha, PAFAH1B1, PAFAHA

Cellular Location: Nucleus Cytoplasm 

Immunogen:
Recombinant protein of human PAFAH1B1

Gene Symbol: PAFAH1B1

Gene ID: 5048

Swiss prot: P43034

Calculated MW: 47kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.