PAFAH1B3 antibody (clone 8C11), anti-human, rat
€435.00
In stock
SKU
AC-AT3170a
Catalog Number: AC-AT3170a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, Ehttps://www.abcepta.com/products/pdf_download/AT3170a-PAFAH1B3-Antibody-monoclonal-M02">Request Information AC-AT3170a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, Ehttps://www.abcepta.com/products/pdf_download/AT3170a-PAFAH1B3-Antibody-monoclonal-M02">Request Information AC-AT3170a">Request Information
Background:
This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
Other Names:
Platelet-activating factor acetylhydrolase IB subunit gamma, PAF acetylhydrolase 29 kDa subunit, PAF-AH 29 kDa subunit, PAF-AH subunit gamma, PAFAH subunit gamma, PAFAH1B3, PAFAHG
Antigen Type:
Recombinant Protein
Gene Name: PAFAH1B3 (HGNC:8576)
Gene ID: 5050
NCBI Accession: NP_001139411.1;NP_001139412.1;NP_002564.1
Primary Accession: Q15102
Other Accession: BC003016
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
Other Names:
Platelet-activating factor acetylhydrolase IB subunit gamma, PAF acetylhydrolase 29 kDa subunit, PAF-AH 29 kDa subunit, PAF-AH subunit gamma, PAFAH subunit gamma, PAFAH1B3, PAFAHG
Antigen Type:
Recombinant Protein
Gene Name: PAFAH1B3 (HGNC:8576)
Gene ID: 5050
NCBI Accession: NP_001139411.1;NP_001139412.1;NP_002564.1
Primary Accession: Q15102
Other Accession: BC003016
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review