PAFAH1B3 Polyclonal Antibody

Background:
This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.

Research Area: Cardiovascular, Metabolism, Neuroscience, Signal transduction

Synonyms:
PA1B3, PAF acetylhydrolase 29 kDa subunit, PAF AH 29 kDa subunit, PAF AH subunit gamma, PAF-AH 29 kDa subunit, PAF-AH subunit gamma, PAFAH subunit gamma, Pafah1b3, PAFAHG, Platelet activating factor acetylhydrolase IB subunit gamma, Platelet activating factor acetylhydrolase isoform Ib gamma subunit (29kD), Platelet activating factor acetylhydrolase isoform Ib gamma subunit 29kDa, Platelet activating factor acetylhydrolase isoform Ib gamma subunit, Platelet-activating factor acetylhydrolase IB subunit gamma

Immunogen: Fusion protein of human PAFAH1B3

Swissprot: Q15102
Gene Accession: BC003016

Calculated MW: 26 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.2 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.