PAFAH2 Polyclonal Antibody

Background:
This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.

Research Area: Metabolism, Signal Transduction

Synonyms:
EC 3.1.1.47, HSD PLA2, HSDPLA2, Platelet activating factor acetylhydrolase 2, Platelet activating factor acetylhydrolase 2 cytoplasmic, platelet-activating factor acetylhydrolase 2, 40kDa, SD PLA2, Serine dependent phospholipase A2

Immunogen: Synthetic peptide of human PAFAH2

Swissprot: Q99487
Gene Accession: NP_000428

Calculated MW: 44 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-161983