PAI-1 Polyclonal Antibody

Background:
serpin family E member 1(SERPINE1) Homo sapiens This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Alternative Names:
SERPINE1, PAI1, PLANH1, Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1

Immunogen: The antiserum was produced against synthesized peptide derived from human PAI-1. AA range:266-315

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 37

GeneID: SERPINE1

Storage: -20°C/1 year

NOTE: For Research Use Only