PAK Gamma monoclonal antibody, anti-human, monkey
€0.00
In stock
SKU
BT-MCA0984
Catalog Number: BT-MCA0984
Size(s): 50μL, 100μL
Isotype: Mouse IgG
Reactivity: human, monkey
Application(s): WB, IHC-p, IF, ICC, ELISA
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG
Reactivity: human, monkey
Application(s): WB, IHC-p, IF, ICC, ELISA
Datasheet
Request Information
Background:
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Research Area: Signal transduction, Cancer, Cell biology, Microbiology
Synonyms: PAK2, Serine, threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6, H4 kinase, p21-activated kinase 2, PAK-2, p58
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Research Area: Signal transduction, Cancer, Cell biology, Microbiology
Synonyms: PAK2, Serine, threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6, H4 kinase, p21-activated kinase 2, PAK-2, p58
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
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