PAK1 polyclonal, anti-human antibody
€295.00
In stock
SKU
AC-ABV11522-100
Catalog Number: AC-ABV11522-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
Request Information
Background:
Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation.
Other Names:
PAK1, PAK-1, p21/Cdc42/Rac1-activated kinase 1. PAK alpha, Alpha-PAK , p65-PAK, MGC130001, MGC130000
Primary Accession: Q13153
Gene Name: PAK1 (HGNC:8590)
Gene ID: 5058
Concentration (mg/ml): 0.2 mg/ml
Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation.
Other Names:
PAK1, PAK-1, p21/Cdc42/Rac1-activated kinase 1. PAK alpha, Alpha-PAK , p65-PAK, MGC130001, MGC130000
Primary Accession: Q13153
Gene Name: PAK1 (HGNC:8590)
Gene ID: 5058
Concentration (mg/ml): 0.2 mg/ml
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