PAK1 polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV11567-100
Catalog Number: AC-ABV11567-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation.
Other Names:
p21/Cdc42/Rac1-activated kinase 1. PAK alpha, Alpha-PAK, p65-PAK
Primary Accession: Q13153
Gene Name: PAK1 (HGNC:8590)
Gene ID: 5058
Concentration (mg/ml): 0.5 mg/ml
Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation.
Other Names:
p21/Cdc42/Rac1-activated kinase 1. PAK alpha, Alpha-PAK, p65-PAK
Primary Accession: Q13153
Gene Name: PAK1 (HGNC:8590)
Gene ID: 5058
Concentration (mg/ml): 0.5 mg/ml
| Is Featured? | No |
|---|
Write Your Own Review