PAK1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: PAKalpha

Cellular Location: Cell junction Cell membrane Cell projection Cytoplasm focal adhesion invadopodium ruffle membrane

Immunogen:
A synthetic peptide of human PAK1

Gene Symbol: PAK1

Gene ID: 5058

Swiss prot: Q13153

Calculated MW: 61kDa

Recommended dilution:
WB 1:500-2000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.