PAK1 Polyclonal Antibody

Background:
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
PAK1, PAKalpha

Immunogen: Recombinant fusion protein of human PAK1 (NP_002567.3).

Swissprot: Q13153
Gene ID: 5058

Calculated MW: 60 kDa/61 kDa
Observed MW: 70 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.