PAK2 Polyclonal Antibody

Background:
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Research Area: Cancer, Cell Biology, Microbiology, Signal Transduction

Synonyms:
PAK2, PAK65, PAKgamma

Immunogen: Recombinant fusion protein of human PAK2 (NP_002568.2).

Swissprot: Q13177
Gene ID: 5062

Calculated MW: 58 kDa
Observed MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.