PAK3 Polyclonal Antibody

Background:
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.

Research Area: Neuroscience, Signal transduction

Synonyms:
PAK3, ARA, MRX30, MRX47, OPHN3, PAK-3, PAK3beta, bPAK, beta-PAK

Immunogen: A synthetic peptide of human PAK3 (NP_001121638.1).

Swissprot: O75914
Gene ID: 5063

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.