PAK4 polyclonal, anti-human, mouse, rat, hamster antibody
€290.00
In stock
SKU
AC-ABV10323-30
Catalog Number: AC-ABV10323-30
Size: 30 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 30 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Several mechanisms that induce PAK activation have been reported. Binding of Rac/cdc42 to the CRIB (or PBD) domain at the N-terminal region of PAK causes autophosphorylation and conformational change of PAK. More recently identified members PAK4, PAK5 and PAK6 have lower sequence similarity with PAK1-3 in the regulatory N-terminal region. It has been demonstrated that phosphorylation of serine 474 of PAK4 may play a pivotal role in the activity and function of PAK4 kinase
Other Names:
PAK-4 , KIAA1142
Primary Accession: O96013
Other Accession: BAF84528
Gene Name: PAK4
Gene ID: 10298
Concentration (mg/ml): 0.5 mg/ml
The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Several mechanisms that induce PAK activation have been reported. Binding of Rac/cdc42 to the CRIB (or PBD) domain at the N-terminal region of PAK causes autophosphorylation and conformational change of PAK. More recently identified members PAK4, PAK5 and PAK6 have lower sequence similarity with PAK1-3 in the regulatory N-terminal region. It has been demonstrated that phosphorylation of serine 474 of PAK4 may play a pivotal role in the activity and function of PAK4 kinase
Other Names:
PAK-4 , KIAA1142
Primary Accession: O96013
Other Accession: BAF84528
Gene Name: PAK4
Gene ID: 10298
Concentration (mg/ml): 0.5 mg/ml
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