PAK4 polyclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP7929a
Catalog Number: AC-AP7929a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01233
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01233
Applications: WB, IHC-P
Datasheet
Request Information
Background:
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Other Names:
Serine/threonine-protein kinase PAK 4, p21-activated kinase 4, PAK-4, PAK4, KIAA1142
Target/Specificity:
This PAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-187 amino acids from the N-terminal region of human PAK4.
Antigen Region:
156-187
Antigen Type: Synthetic Peptide
Gene Name: PAK4
Gene ID: 10298
Primary Accession: O96013
NCBI Accession: NP_001014831.1;NP_001014832.1;NP_001014834.1;NP_001014835.1;NP_005875.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Other Names:
Serine/threonine-protein kinase PAK 4, p21-activated kinase 4, PAK-4, PAK4, KIAA1142
Target/Specificity:
This PAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-187 amino acids from the N-terminal region of human PAK4.
Antigen Region:
156-187
Antigen Type: Synthetic Peptide
Gene Name: PAK4
Gene ID: 10298
Primary Accession: O96013
NCBI Accession: NP_001014831.1;NP_001014832.1;NP_001014834.1;NP_001014835.1;NP_005875.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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