PAK5 polyclonal, anti-human
€0.00
In stock
SKU
AC-AP7930a
Catalog Number: AC-AP7930a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1235
Applications: IHC-P, WB, IHC-P-Leica
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1235
Applications: IHC-P, WB, IHC-P-Leica
Datasheet
Request Information
Background:
PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.
Other Names:
Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7, PAK7, KIAA1264, PAK5
Target/Specificity:
This PAK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from human PAK5.
Antigen Region:
168-198
Antigen Type: Synthetic Peptide
Gene Name: PAK5 (HGNC:15916)
Gene ID: 57144
Primary Accession: Q9P286
NCBI Accession: NP_065074.1;NP_817127.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.
Other Names:
Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7, PAK7, KIAA1264, PAK5
Target/Specificity:
This PAK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from human PAK5.
Antigen Region:
168-198
Antigen Type: Synthetic Peptide
Gene Name: PAK5 (HGNC:15916)
Gene ID: 57144
Primary Accession: Q9P286
NCBI Accession: NP_065074.1;NP_817127.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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