PAK6 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12164c
Background:
This gene encodes a member of the p21-activated kinase(PAK) family. The proteins of this family are Rac/Cdc42-associatedSte20-like Ser/Thr protein kinases, characterized by a highlyconserved amino-terminal Cdc42/Rac interactive binding (CRIB)domain and a carboxyl-terminal kinase domain. PAK kinases areimplicated in the regulation of a number of cellular processes,including cytoskeleton rearrangement, apoptosis and the MAP kinasesignaling pathway. The protein encoded by this gene was found tointeract with androgen receptor (AR), which is a steroidhormone-dependent transcription factor that is important for malesexual differentiation and development. This gene was found to behighly expressed in testis and prostate tissues and the encodedprotein was shown to cotranslocate into the nucleus with AR inresponse to androgen. Alternatively spliced transcript variantsencoding the same protein have been found for this gene. [providedby RefSeq].
Other Names:
Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6, PAK6, PAK5
Gene Name: PAK6
Gene ID: 106821730;56924
Primary Accession: Q9NQU5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the p21-activated kinase(PAK) family. The proteins of this family are Rac/Cdc42-associatedSte20-like Ser/Thr protein kinases, characterized by a highlyconserved amino-terminal Cdc42/Rac interactive binding (CRIB)domain and a carboxyl-terminal kinase domain. PAK kinases areimplicated in the regulation of a number of cellular processes,including cytoskeleton rearrangement, apoptosis and the MAP kinasesignaling pathway. The protein encoded by this gene was found tointeract with androgen receptor (AR), which is a steroidhormone-dependent transcription factor that is important for malesexual differentiation and development. This gene was found to behighly expressed in testis and prostate tissues and the encodedprotein was shown to cotranslocate into the nucleus with AR inresponse to androgen. Alternatively spliced transcript variantsencoding the same protein have been found for this gene. [providedby RefSeq].
Other Names:
Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6, PAK6, PAK5
Gene Name: PAK6
Gene ID: 106821730;56924
Primary Accession: Q9NQU5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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