PAK6 polyclonal, anti-human, mouse

Background:
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Synonyms: PAK5

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human PAK6

Gene Symbol: PAK6

Gene ID: 56924

Swiss prot: Q9NQU5

Calculated MW: 75/70kDa

Recommended dilution:
IHC 1:50-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.