PAKα/β/γ (phospho Thr423/402/421) Polyclonal Antibody

PAKα/β/γ (phospho Thr423/402/421) Polyclonal Antibody

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In stock
SKU
ELK-ES6462
Catalog Number: ELK-ES6462
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
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Background:
p21 (RAC1) activated kinase 1(PAK1) Homo sapiens This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

Alternative Names:
PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK

Immunogen: The antiserum was produced against synthesized peptide derived from human PAK1/2/3 around the phosphorylation site of Thr423/402/421. AA range:391-440

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 60

GeneID: PAK1/PAK2/PAK3

Storage: -20°C/1 year

NOTE: For Research Use Only
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