PAKγ (phospho Ser192) Polyclonal Antibody

Background:
p21 (RAC1) activated kinase 2(PAK2) Homo sapiens The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],

Alternative Names:
PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58

Immunogen: The antiserum was produced against synthesized peptide derived from human PAK2 around the phosphorylation site of Ser192. AA range:158-207

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 58

GeneID: PAK2

Storage: -20°C/1 year

NOTE: For Research Use Only