Pancreastatin polyclonal, anti-human, pig

Quantity: 100 µl

Background:
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

Synonyms:
CGA

Isotype: Rabbit Polyclonal

Immunogen:
Synthetic pancreastatin

Form: Serum containing 0.1% sodium azide

Specificity:
Pancreastatin

Reactivity: human, pig

Applications: Immunocytochemistry, Immunohistochemistry, suitable for frozen and paraffin sections, no pretreatment

Working DIlution: 1:25 to 1:50 for immunohistochemistry

Positive Control:
Pancreas

Storage: 2-8C for immediate use, or at -20C (aliquot)

References:
- Chen D et al (1994) Gastroenterology 107: 18-27