Pancreatic Polypeptide
€265.00
In stock
SKU
350327
Protein Family: Hormones
Pathway and Disease: Endocrine System, Metabolic Disorders
Alternate Names: Pancreatic prohormone; Pancreatic polypeptide; PP; Obinepitide; PPY; PNP; Pancreatic hormone
Accession No.: P01298
Description:
The pancreatic prohormone (Pancreatic Polypeptide or PPY) is synthesized in the pancreatic islets of Langherans. PPY regulates pancreatic and gastrointestinal functions. PPY is cleaved into 2 chains, a 36-aa pancreatic hormone (PH, Cat. No. 350327, human sequence) and a 20-aa pancreatic icosapeptide (PI). Obinepitide, a PPY derivative with Gln63, is tested in clinical trials for the treatment of obesity.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 4181.8 g/mol
Sequence:
Human: H-Ala-Pro-Leu-Glu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 or H-APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2
Composition:
C185H287N53O54S2
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Pathway and Disease: Endocrine System, Metabolic Disorders
Alternate Names: Pancreatic prohormone; Pancreatic polypeptide; PP; Obinepitide; PPY; PNP; Pancreatic hormone
Accession No.: P01298
Description:
The pancreatic prohormone (Pancreatic Polypeptide or PPY) is synthesized in the pancreatic islets of Langherans. PPY regulates pancreatic and gastrointestinal functions. PPY is cleaved into 2 chains, a 36-aa pancreatic hormone (PH, Cat. No. 350327, human sequence) and a 20-aa pancreatic icosapeptide (PI). Obinepitide, a PPY derivative with Gln63, is tested in clinical trials for the treatment of obesity.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 4181.8 g/mol
Sequence:
Human: H-Ala-Pro-Leu-Glu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 or H-APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2
Composition:
C185H287N53O54S2
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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