Pancreatic Polypeptide (clone 6), anti-human
€1,070.00
In stock
SKU
250242
Protein Family: Hormones,Receptors and Channels
Pathway and Disease: Endocrine System,Signaling Molecules and Interaction
Description:
Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors. This antibody binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.
Alternate Names: Pancreatic polypeptide, PP, Obinepitide
Application Notes: Product Cat. No. 250242 binds free PP in solution. Product Cat. No. 250242 reacts in ELISA with PP coated directly onto the microtiter well. E: 1:8,000
Accession No.: P01298
Antigen: Synthetic human PP coupled to carrier with glutaraldehyde
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Endocrine System,Signaling Molecules and Interaction
Description:
Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors. This antibody binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.
Alternate Names: Pancreatic polypeptide, PP, Obinepitide
Application Notes: Product Cat. No. 250242 binds free PP in solution. Product Cat. No. 250242 reacts in ELISA with PP coated directly onto the microtiter well. E: 1:8,000
Accession No.: P01298
Antigen: Synthetic human PP coupled to carrier with glutaraldehyde
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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