PANX1(NT) polyclonal, anti-human, mouse antibody
€355.00
In stock
SKU
AC-ABV10910-100
Catalog Number: AC-ABV10910-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, E
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, E
Datasheet
Request Information
Background:
The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Other Names:
Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028
Primary Accession: Q96RD7
Gene Name: PANX1 (HGNC:8599)
Gene ID: 24145
Concentration (mg/ml): 1 mg/ml
The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Other Names:
Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028
Primary Accession: Q96RD7
Gene Name: PANX1 (HGNC:8599)
Gene ID: 24145
Concentration (mg/ml): 1 mg/ml
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