PAPPA Polyclonal Antibody

Background:
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.

Research Area: Cell Biology, Cardiovascular

Synonyms:
ASBABP2, Aspecific BCL2 ARE binding protein 2, Differentially placenta 1 expressed protein, DIPLA1, EC 3.4.24.79, IGF dependent IGFBP 4 protease, IGF-dependent IGFBP-4 protease, IGFBP 4ase, IGFBP-4ase, IGFBP4ase, Insulin like growth factor dependent IGF binding protein 4 protease, Insulin-like growth factor-dependent IGF-binding protein 4 protease, PAPA, PAPP A, PAPP-A, PAPP1, PAPPA, PAPPA1, Pappalysin 1 precursor, Pappalysin-1, Pregnancy Associated Plasma Protein A, Pregnancy associated plasma protein A pappalysin 1, Pregnancy-associated plasma protein A

Immunogen: Synthetic peptide of human PAPPA

Swissprot: Q13219
Gene Accession: NP_002572

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-47300/sc-47301/sc-50518