PAR-4 polyclonal, anti-human
€469.00
In stock
SKU
251943
Protein Family: Transcription Factors
Pathway and Disease: Cancers, Cell Growth and Death, Neurodegenerative Disorders, Signaling Molecules and Interaction
Description:
Prostate apoptosis response 4 protein (PAR4) is a pro-apoptotic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. PAR-4 induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NFkB transcriptional activity. PAR-4 is widely expressed but is found elevated in various neurodegenerative diseases.
Alternate Names: PRKC apoptosis WT1 regulator protein, prostate apoptosis response 4 protein, PAWR, PAR4
Application Notes: E: 1:20,000-1:80,000; WB: 1:200-1:1,000
Accession No.: Q96IZ0
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PAR-4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cancers, Cell Growth and Death, Neurodegenerative Disorders, Signaling Molecules and Interaction
Description:
Prostate apoptosis response 4 protein (PAR4) is a pro-apoptotic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. PAR-4 induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NFkB transcriptional activity. PAR-4 is widely expressed but is found elevated in various neurodegenerative diseases.
Alternate Names: PRKC apoptosis WT1 regulator protein, prostate apoptosis response 4 protein, PAWR, PAR4
Application Notes: E: 1:20,000-1:80,000; WB: 1:200-1:1,000
Accession No.: Q96IZ0
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PAR-4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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