PAR6G polyclonal antibody, anti-human, mouse

Background:
The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.,Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.,Belongs to the PAR6 family.,Contains 1 OPR domain.,Contains 1 PDZ (DHR) domain.,Contains 1 pseudo-CRIB domain.,subunit:Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ.,tissue specificity:Widely expressed, with a higher expression in fetal and adult kidney.,

Research Area: Cell biology, Signal transduction

Synonyms: Partitioning defective 6 homolog gamma , PAR-6 gamma, PAR6D

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year