Parafibromin polyclonal, anti-human, mouse, rat, xenopus

Protein Family: Transcription Factors

Pathway and Disease: Cancers, Cell Growth and Death, Endocrine System, Transcription

Description:
Parafibromin (CDC73) is a tumor suppressor involved in transcriptional and post-transcriptional control pathways, such as cell cycle progression through the regulation of cyclin D1/PRAD1 expression. Defects in CDC73 are the cause of parathyroid gland tumors.

Alternate Names: Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein, CDC73, C1orf28, HRPT2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500

Accession No.: Q6P1J9, NP_078805

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human parafibromin.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by saturated sodium sulfate precipitation.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.