Parathyroid Hormone (N-Terminal) (PTH) [clone 3H9], anti-human, predicted to react with mouse, rat, rabbit, cow, dog, pig, deer and orangutan

Description: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.Localization: cytoplasm, secretedDilution: 100-300Positive Control: parathyroid glandHIER: citrate pH6.0Status: RUO