PARD6A polyclonal, anti-human, mouse

Background:
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40

Cellular Location: Cell junction Cell membrane Cell projection Cytoplasm ruffle tight junction

Immunogen:
A synthetic peptide of human PARD6A

Gene Symbol: PARD6A

Gene ID: 50855

Swiss prot: Q9NPB6

Calculated MW: 37kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.