PARD6A Polyclonal Antibody

Background:
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells

Synonyms:
0710008C04Rik, 2610010A15Rik, Par 6 partitioning defective 6 C elegans homolog alpha, Par 6 partitioning defective 6 homolog alpha, Par 6 partitioning defective 6 homolog alpha C elegans, PAR 6A, PAR-6 alpha, PAR-6, par-6 family cell polarity regulator alpha, PAR-6A, PAR6, PAR6A, PAR6alpha, PAR6C, Pard6a, Partitioning defective 6 homolog alpha, partitioning-defective protein 6, partitioning-defective protein 6, C. elegans, homolog of, alpha, Tax interacting protein 40, Tax interaction protein 40, TAX40, TIP 40, TIP-40, TIP40

Immunogen: Recombinant protein of human PARD6A

Swissprot: Q9NPB6
Gene Accession: BC015626

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-14401/sc-14403/sc-14405/sc-33898/sc-25525