PARK2 antibody (clone 1H4), anti-human

Background:
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Other Names:
E3 ubiquitin-protein ligase parkin, 632-, Parkinson juvenile disease protein 2, Parkinson disease protein 2, PARK2, PRKN

Antigen Type:
Recombinant Protein

Gene Name: PRKN (HGNC:8607)
Gene ID: 5071
NCBI Accession: NP_004553.2;NP_054642.2;NP_054643.2
Primary Accession: O60260
Other Accession: BC022014
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .