PARK2 polyclonal, anti-human, mouse

Background:
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Synonyms: PRKN, PARK2, AR-JP, LPRS2, PDJ,

Cellular Location: Cytoplasm Endoplasmic reticulum Mitochondrion Nucleus cytosol

Immunogen:
Recombinant protein of human PARK2

Gene Symbol: PARK2

Gene ID: 5071

Swiss prot: O60260

Calculated MW: 52kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.