Parkin Polyclonal Antibody

Background:
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience

Synonyms:
PRKN, AR-JP, LPRS2, PARK2, PDJ, Parkin

Immunogen: Recombinant fusion protein of human Parkin

Swissprot: O60260
Gene ID: 5071

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.