Parkin polyclonal (N-term), anti-human
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In stock
SKU
AC-AP6402a
Catalog Number: AC-AP6402a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7371
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7371
Applications: WB
Datasheet
Request Information
Background:
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function.
Other Names:
E3 ubiquitin-protein ligase parkin, 632-, Parkinson juvenile disease protein 2, Parkinson disease protein 2, PARK2, PRKN
Target/Specificity:
This Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human Parkin.
Antigen Region:
111-140
Antigen Type: Synthetic Peptide
Gene Name: PRKN (HGNC:8607)
Gene ID: 5071
Primary Accession: O60260
NCBI Accession: NP_004553.2;NP_054642.2;NP_054643.2
Other Accession: NP_004553
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function.
Other Names:
E3 ubiquitin-protein ligase parkin, 632-, Parkinson juvenile disease protein 2, Parkinson disease protein 2, PARK2, PRKN
Target/Specificity:
This Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human Parkin.
Antigen Region:
111-140
Antigen Type: Synthetic Peptide
Gene Name: PRKN (HGNC:8607)
Gene ID: 5071
Primary Accession: O60260
NCBI Accession: NP_004553.2;NP_054642.2;NP_054643.2
Other Accession: NP_004553
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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