PARL (clone 8C4B2;1H12E10), anti-human

PARL (clone 8C4B2;1H12E10), anti-human

€421.00
In stock
SKU
252797
Catalog Nr.: 252797
Size: 0.1 ml
Isotype: Mouse IgG2b
Applications: WB
Datasheet
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Protein Family: Enzymes, Peptidases

Pathway and Disease: Cell Growth and Death

Description:
PARL (Presenilin Associated Rhomboid-Like protein) is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This protein may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this protein has been associated with increased risk for type 2 diabetes.

Alternate Names: Presenilins-associated rhomboid-like protein, mitochondrial, Mitochondrial intramembrane cleaving protease, PARL, Pbeta, PSARL, PARL

Application Notes: WB: 1:500-1:2000

Accession No.: Q9H300

Antigen: Purified recombinant fragment of PARL(aa112-167) expressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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