PARL (clone 8C4B2), anti-human

PARL (clone 8C4B2), anti-human

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In stock
SKU
BT-MCA4436
Catalog Number: BT-MCA4436
Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity: human
Application(s):
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Background:
PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Metabolism, Neuroscience, Cell biology, Cancer

Synonyms: PSARL, PSARL1, RHBDS1

Immunogen: Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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