PARL Polyclonal Antibody

Background:
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience

Synonyms:
PARL, PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1

Immunogen: Recombinant fusion protein of human PARL (NP_001032728.1).

Swissprot: Q9H300
Gene ID: 55486

Calculated MW: 36 kDa/42 kDa
Observed MW: 49 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.