PARP-1 (Acetyl-K521) polyclonal antibody, anti-human, mouse, rat
€0.00
In stock
SKU
BT-AP12792
Catalog Number: BT-AP12792
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): WB, ELISA
Datasheet
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Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): WB, ELISA
Datasheet
Request Information
Background:
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Research Area: Epigenetics and nuclear signaling, Signal transduction
Synonyms: PARP-1 , Poly [ADP-ribose, polymerase 1, PARP-1, EC 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD, + ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose, synthase 1
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Research Area: Epigenetics and nuclear signaling, Signal transduction
Synonyms: PARP-1 , Poly [ADP-ribose, polymerase 1, PARP-1, EC 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD, + ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose, synthase 1
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
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