PARP-14 polyclonal, anti-human
€422.00
In stock
SKU
251941
Protein Family: Transcription Factors, Enzymes
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
Poly [ADP-ribose] polymerase 14 (PARP-14) functions as a transcriptional switch for Stat6-dependent gene induction. In the absence of a signal, PARP-14 acts as a transcriptional repressor by recruiting histone deacetylases (HDACs). In contrast, in the presence of IL-4 the catalytic activity of PARP-14 facilitates Stat6 binding to the promoter, and release of HDACs so as to activate transcription.
Alternate Names: Poly [ADP-ribose] polymerase 14, PARP-14, B aggressive lymphoma protein 2, PARP14, BAL2, KIAA1268
Application Notes: E: 1:10,000-1:40,000; WB: 1:100-1:500
Accession No.: Q460N5
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PARP-14.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
Poly [ADP-ribose] polymerase 14 (PARP-14) functions as a transcriptional switch for Stat6-dependent gene induction. In the absence of a signal, PARP-14 acts as a transcriptional repressor by recruiting histone deacetylases (HDACs). In contrast, in the presence of IL-4 the catalytic activity of PARP-14 facilitates Stat6 binding to the promoter, and release of HDACs so as to activate transcription.
Alternate Names: Poly [ADP-ribose] polymerase 14, PARP-14, B aggressive lymphoma protein 2, PARP14, BAL2, KIAA1268
Application Notes: E: 1:10,000-1:40,000; WB: 1:100-1:500
Accession No.: Q460N5
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PARP-14.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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