PARP (clone 7A10), anti-human
€478.00
In stock
SKU
252976
Protein Family: Transcription Factors, Enzymes
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
PARP1 (Poly [ADP-ribose] polymerase 1) is a glycosyltransferase, involved in the base excision repair (BER) pathway. PARP1 is catalyzing the poly ADP-ribosylation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Alternate Names: PARP1, Poly [ADP-ribose] polymerase 1, PARP-1, ADPRT, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthetase 1, ADPRT, PPOL
Application Notes: WB: 1:500-1:2000; FC: 1:200-1:400
Accession No.: P09874
Antigen: Synthetic peptide of human PARP, conjugated to KLH.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
PARP1 (Poly [ADP-ribose] polymerase 1) is a glycosyltransferase, involved in the base excision repair (BER) pathway. PARP1 is catalyzing the poly ADP-ribosylation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Alternate Names: PARP1, Poly [ADP-ribose] polymerase 1, PARP-1, ADPRT, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthetase 1, ADPRT, PPOL
Application Notes: WB: 1:500-1:2000; FC: 1:200-1:400
Accession No.: P09874
Antigen: Synthetic peptide of human PARP, conjugated to KLH.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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