PARP (clone 7A10), anti-human

PARP (clone 7A10), anti-human

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In stock
SKU
BT-MCA3124
Catalog Number: BT-MCA3124
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, FCM
Datasheet
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Background:
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Research Area: Others

Synonyms: PARP, PPOL, ADPRT, ADPRT1, PARP-1, pADPRT-1, PARP1

Immunogen: Synthetic peptide of human PARP, conjugated to KLH.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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