PARP1 antibody (clone 3G4), anti-human
€435.00
In stock
SKU
AC-AT3183a
Catalog Number: AC-AT3183a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT3183a">Request Information
Background:
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Other Names:
Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, PARP1, ADPRT, PPOL
Antigen Type:
Recombinant Protein
Gene Name: PARP1 {ECO:0000303|PubMed:21680843, ECO:0000312|HGNC:HGNC:270}
Gene ID: 142
NCBI Accession: NP_001609.2
Primary Accession: P09874
Other Accession: BC037545
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Other Names:
Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, PARP1, ADPRT, PPOL
Antigen Type:
Recombinant Protein
Gene Name: PARP1 {ECO:0000303|PubMed:21680843, ECO:0000312|HGNC:HGNC:270}
Gene ID: 142
NCBI Accession: NP_001609.2
Primary Accession: P09874
Other Accession: BC037545
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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