PARP11 Polyclonal Antibody

Background:
Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
5330431N24Rik, AI851877, C12orf6, DKFZp779H0122, HIN1L, MIB006, OTTMUSP00000027219, Poly (ADP ribose) polymerase family member 11, RGD1561791

Immunogen: Recombinant protein of human PARP11

Swissprot: Q9NR21
Gene Accession: BC017569

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-82967/sc-82968/sc-130836