PARP2 C-terminal region polyclonal, anti-human, mouse, rat, rabbit, dog, guinea pig, horse, bovine

Background:
This is a rabbit polyclonal antibody against PARP2. It was validated on Western Blot by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein.

Other Names:
Poly [ADP-ribose] polymerase 2, PARP-2, hPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, ARTD2, NAD(+) ADP-ribosyltransferase 2, ADPRT-2, Poly[ADP-ribose] synthase 2, pADPRT-2, PARP2, ADPRT2, ADPRTL2

Target/Specificity:
PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Immunogen:
The immunogen for Anti-PARP2 antibody is: synthetic peptide directed towards the C-terminal region of Human PARP2

Gene Name:
PARP2 {ECO:0000303|PubMed:20092359, ECO:0000312|HGNC:HGNC:272}
Gene Name:
10038
Swissprot ID: Q9UGN5-2
NCBI Accession:
NP_001036083
Primary Accession: Q9UGN5
Other Accession: Q9UGN5-2;NP_001036083;NM_001042618
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.