PARS2 Polyclonal Antibody

Background:
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
DKFZp727A071, EC 6.1.1.15, MGC14416, MGC19467, mitochondrial, MT-PRORS, Pars2, Probable proline tRNA ligase mitochondrial, Probable prolyl-tRNA synthetase, probable prolyl-tRNA synthetase, mitochondrial, proline tRNA ligase 2, mitochondrial (putative), Proline--tRNA ligase, prolyl-tRNA synthetase 2, mitochondrial (putative), ProRS, SYPM

Immunogen: Fusion protein of human PARS2

Swissprot: Q7L3T8
Gene Accession: BC007956

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.