Parvalbumin α polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60382
Background:
Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif. The AB domain houses a two amino-acid deletion in the loop region, whereas domains CD and EF contain the N-terminal and C-terminal, respectively. Calcium binding proteins like parvalbumin play a role in many physiological processes, namely cell-cycle regulation, second messenger production, muscle contraction, organization of microtubules and vision. Parvalbumin expressing neurons have also been found to be in connection with various areas of clinical interest such as Alzheimer’s disease, nervous system disorders, age-related cognitive defects and some forms of cancer.
Alternative Name:
Parvalbumin alpha, PVALB, Parvalbumin-α
Application Dilution: WB: 1:500~1:1000
Specificity: Parvalbumin α polyclonal antibody detects endogenous levels of Parvalbumin α protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Parvalbumin α.
MW: ~ 15 kDa
Swis Prot.: P20472
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif. The AB domain houses a two amino-acid deletion in the loop region, whereas domains CD and EF contain the N-terminal and C-terminal, respectively. Calcium binding proteins like parvalbumin play a role in many physiological processes, namely cell-cycle regulation, second messenger production, muscle contraction, organization of microtubules and vision. Parvalbumin expressing neurons have also been found to be in connection with various areas of clinical interest such as Alzheimer’s disease, nervous system disorders, age-related cognitive defects and some forms of cancer.
Alternative Name:
Parvalbumin alpha, PVALB, Parvalbumin-α
Application Dilution: WB: 1:500~1:1000
Specificity: Parvalbumin α polyclonal antibody detects endogenous levels of Parvalbumin α protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Parvalbumin α.
MW: ~ 15 kDa
Swis Prot.: P20472
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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